VWA3A-derived ependyma promoter drives increased therapeutic protein secretion into the CSF

VWA3A-derived ependyma promoter drives increased therapeutic protein secretion into the CSF

Recombinant adeno-associated viral vectors (rAAVs) are a promising strategy to treat neurodegenerative diseases because of their ability to infect non-dividing cells and confer long-term transgene expression. Despite an ever-growing library of capsid variants, widespread delivery of AAVs in the adul...

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Main Authors: Ellie M. Carrell (Author), Yong Hong Chen (Author), Paul T. Ranum (Author), Stephanie L. Coffin (Author), Larry N. Singh (Author), Luis Tecedor (Author), Megan S. Keiser (Author), Eloise Hudry (Author), Bradley T. Hyman (Author), Beverly L. Davidson (Author)
Format: Book
Published: Elsevier, 2023-09-01T00:00:00Z.
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3rd Floor Main Library

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