VWA3A-derived ependyma promoter drives increased therapeutic protein secretion into the CSF
Recombinant adeno-associated viral vectors (rAAVs) are a promising strategy to treat neurodegenerative diseases because of their ability to infect non-dividing cells and confer long-term transgene expression. Despite an ever-growing library of capsid variants, widespread delivery of AAVs in the adul...
Saved in:
Main Authors: | Ellie M. Carrell (Author), Yong Hong Chen (Author), Paul T. Ranum (Author), Stephanie L. Coffin (Author), Larry N. Singh (Author), Luis Tecedor (Author), Megan S. Keiser (Author), Eloise Hudry (Author), Bradley T. Hyman (Author), Beverly L. Davidson (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2023-09-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Secondary Brain Injury Following Neonatal Intraventricular Hemorrhage: The Role of the Ciliated Ependyma
by: William Dawes, et al.
Published: (2022) -
Cas9 editing of ATXN1 in a spinocerebellar ataxia type 1 mice and human iPSC-derived neurons
by: Kelly J. Fagan, et al.
Published: (2024) -
Temporal restriction of Cas9 expression improves CRISPR-mediated deletion efficacy and fidelity
by: Jesse A. Weber, et al.
Published: (2024) -
VMHdm/cSF-1 neuronal circuits regulate skeletal muscle PGC1-α via the sympathoadrenal drive
by: Takuya Yoshida, et al.
Published: (2023) -
Antibiotic impregnated catheters and intrathecal antibiotics for CSF shunt infection prevention in children undergoing low-risk CSF shunt surgery
by: Stacey Podkovik, et al.
Published: (2024)