An in-vitro cocktail assay for assessing compound-mediated inhibition of six major cytochrome P450 enzymes

An efficient screening assay was developed and validated for simultaneous assessment of compound-mediated inhibition of six major human cytochrome P450 (CYP) enzymes. This method employed a cocktail of six probe substrates (i.e., phenacetin, amodiaquine, diclofenac, S-mephenytoin, dextromethorphan a...

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Main Authors: Jing-Jing Wang (Author), Jian-Jun Guo (Author), Jenny Zhan (Author), Hai-Zhi Bu (Author), Jiunn H. Lin (Author)
Format: Book
Published: Elsevier, 2014-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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