An in-vitro cocktail assay for assessing compound-mediated inhibition of six major cytochrome P450 enzymes
An efficient screening assay was developed and validated for simultaneous assessment of compound-mediated inhibition of six major human cytochrome P450 (CYP) enzymes. This method employed a cocktail of six probe substrates (i.e., phenacetin, amodiaquine, diclofenac, S-mephenytoin, dextromethorphan a...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2014-08-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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