Characterization of the Paracoccidioides Hypoxia Response Reveals New Insights into Pathogenesis Mechanisms of This Important Human Pathogenic Fungus.

• Main Authors: Patrícia de Sousa Lima (Author), Dawoon Chung (Author), Alexandre Melo Bailão (Author), Robert A Cramer (Author), Célia Maria de Almeida Soares (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hypoxic microenvironments are generated during fungal infection. It has been described that to survive in the human host, fungi must also tolerate and overcome in vivo microenvironmental stress conditions including low oxygen tension; however nothing is known how Paracoccidioides species respond to...