Estimating peptide half‐life in serum from tunable, sequence‐related physicochemical properties

Abstract Proteolytic instability is a critical limitation for peptide‐based products. Although significant efforts are devoted to stabilize sequences against proteases/peptidases in plasma/serum, such approaches tend to be rather empirical, unspecific, time‐consuming, and frequently not cost‐effecti...

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Main Authors: Marco Cavaco (Author), Javier Valle (Author), Isabel Flores (Author), David Andreu (Author), Miguel A. R. B. Castanho (Author)
Format: Book
Published: Wiley, 2021-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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