THE INVESTIGATION OF INFLUENCE OF GENETIC PROFILE ON THE EFFICACY AND SAFETY OF HALOPERIDOL IN PATIENTS WITH ALCOHOL DEPENDENCE

• Main Authors: M. S. Zastrozhin (Author), E. A. Grishina (Author), D. A. Sychev (Author), L. M. Savchenko (Author), E. A. Bryun (Author), M. V. Prudnikova (Author), O. M. Saraeva (Author), V. V. Trofimov (Author)
• Format: Book
• Published: SINAPS LLC, 2016-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In case of patients with alcohol addiction haloperidol is used to control the exacerbation of the addiction, but the empirical dose selection of haloperidol often results in adverse side effects. Enzyme CYP2D6, which has encoded by gene CYP2D6 has high variability of activity, which depend from poly...