Identification and Analysis of the Role of Superoxide Dismutases Isoforms in the Pathogenesis of Paracoccidioides spp.

• Main Authors: Diana Tamayo (Author), José F Muñoz (Author), Ángela Lopez (Author), Martha Urán (Author), Juan Herrera (Author), Clayton L Borges (Author), Ángela Restrepo (Author), Celia M Soares (Author), Carlos P Taborda (Author), Agostinho J Almeida (Author), Juan G McEwen (Author), Orville Hernández (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The ability of Paracoccidioides to defend itself against reactive oxygen species (ROS) produced by host effector cells is a prerequisite to survive. To counteract these radicals, Paracoccidioides expresses, among different antioxidant enzymes, superoxide dismutases (SODs). In this study, we identifi...