Platelet-activating factor mediates trinitrobenzene induced dysmotility in the left colon

• Main Authors: W. E. Longo (Author), J. Standeven (Author), B. Chandel (Author), Y. Deshpande (Author), A. M. Vernava (Author), D. Kaminski (Author)
• Format: Book
• Published: Hindawi Limited, 1995-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We investigated whether TNB alters colonic tissue levels of PAF at the expense of changes in colonic motility in the isolated perfused rabbit left colon. Colonic inflammation was induced by the intracolonic administration of 0.25 ml of 50% ethanol containing 30 mg of trinitrobenzene. Strain gauge tr...