Grapefruit Flavonoid Naringenin Sex-Dependently Modulates Action Potential in an In Silico Human Ventricular Cardiomyocyte Model

• Główni autorzy: Henry Sutanto (Autor), Decsa Medika Hertanto (Autor), Hendri Susilo (Autor), Citrawati Dyah Kencono Wungu (Autor)
• Format: Książka
• Wydane: MDPI AG, 2022-08-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Recent in vitro studies showed that grapefruit (<i>Citrus</i> × <i>paradisi</i>) flavonoid naringenin alters the function of cardiac ion channels. Here, we explored the effect of naringenin on cardiomyocyte action potentials (APs) using a detailed in silico model of ventricul...