Optimized Expression and Purification of Humbug in Pichia pastoris and Its Monoclonal Antibody Preparation

• Egile Nagusiak: Ting HUYAN (Egilea), Ruihua TANG (Egilea), Jing LI (Egilea), Qi LI (Egilea), Xiaoping XUE (Egilea), Hui YANG (Egilea)
• Formatua: Liburua
• Argitaratua: Tehran University of Medical Sciences, 2015-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Background: The humbug gene is a truncated isoform of Aspartyl β-hydroxylase (ASPH) gene that is overexpressed in many human malignancies. In recent years, since humbug has received increasing attention, it is considered as a potential therapeutic molecular target. Therefore, it is necessary for pre...