Blood-stage malaria vaccines: post-genome strategies for the identification of novel vaccine candidates

• Main Authors: Edward H. Ntege (Author), Eizo Takashima (Author), Masayuki Morita (Author), Hikaru Nagaoka (Author), Tomoko Ishino (Author), Takafumi Tsuboi (Author)
• Formato: Libro
• Publicado: Taylor & Francis Group, 2017-08-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Introduction: An efficacious malaria vaccine is necessary to advance the current control measures towards malaria elimination. To-date, only RTS,S/AS01, a leading pre-erythrocytic stage vaccine completed phase 3 trials, but with an efficacy of 28-36% in children, and 18-26% in infants, that waned ov...