Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and glucose intolerance by modulating bile acid metabolism in hamsters

• Main Authors: Lulu Sun (Author), Yuanyuan Pang (Author), Xuemei Wang (Author), Qing Wu (Author), Huiying Liu (Author), Bo Liu (Author), George Liu (Author), Min Ye (Author), Wei Kong (Author), Changtao Jiang (Author)
• Format: Book
• Published: Elsevier, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Since metabolic process differs between humans and mice, studies were performed in hamsters, which are generally considered to be a more appropriate animal model for studies of obesity-related metabolic disorders. The modulation of gut microbiota, bile acids and the farnesoid X receptor (FXR) axis i...