Halofuginone Attenuates Osteoarthritis by Rescuing Bone Remodeling in Subchondral Bone Through Oral Gavage

• Главные авторы: Wenbo Mu (Автор), Boyong Xu (Автор), Hairong Ma (Автор), Jiao Li (Автор), Baochao Ji (Автор), Zhendong Zhang (Автор), Abdusami Amat (Автор), Li Cao (Автор)
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• Опубликовано: Frontiers Media S.A., 2018-03-01T00:00:00Z.
• Предметы: article
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Osteoarthritis (OA) is a common debilitating joint disorder worldwide without effective medical therapy. Articular cartilage and subchondral bone act in concert as a functional unit with the onset of OA. Halofuginone is an analog of the alkaloid febrifugine extracted from the plant Dichroa febrifuga...