A Simple Method to Extract Whole Apolipoproteins for the Preparation of Discoidal Recombined High Density Lipoproteins as Bionic Nanocarriers for Drug Delivery

• Main Authors: Wenli Zhang (Author), Ji Wang (Author), Junting Jia (Author), Liang Chen (Author), Zimei Wu (Author), Jianping Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: To develop a simple method to extract the whole apolipoproteins (apo) including apoA-I in native high density lipoproteins (HDLs) and prepare discoidal Tanshinone IIA-loaded reconstituted HDL (TA-rHDLs) as a dual functional drug delivery system with plaque-site target and therapeutic promis...