Evaluation of the genomic DNA extracted from formalin-fixed, paraffin-embedded oral samples archived for the past 40-years Avaliação do DNA genômico obtido de biópsias de boca embebidas em parafina e arquivadas por até 40 anos

• Main Authors: Tatiana Nayara Libório (Author), Adriana Etges (Author), Adriana da Costa Neves (Author), Ricardo Alves Mesquita (Author), Fábio Daumas Nunes (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2005-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: The most common human archival specimens are formalin-fixed, paraffin-embedded tissues (PETs). DNA can be extracted from PETs, but sometimes, it is unsuitable for molecular techniques as slow degradation of DNA occurs with time. OBJECTIVE: The aim of this study was to verify and discuss...