Licorice root extract and magnesium isoglycyrrhizinate protect against triptolide-induced hepatotoxicity via up-regulation of the Nrf2 pathway

• Main Authors: Qin-You Tan (Author), Qian Hu (Author), Sheng-Nan Zhu (Author), Lu-Lu Jia (Author), Juan Xiao (Author), Hua-Zhen Su (Author), Shao-Yuan Huang (Author), Jing Zhang (Author), Junfei Jin (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Triptolide, the predominant biologically active component of the Chinese herb Tripterygium wilfordii Hook f., possesses numerous pharmacological activities, including anti-inflammatory, anti-fertility, anti-neoplastic, and immunosuppressive effects. However, toxicity and severe adverse effects, part...