Impact of IgG subclass on molecular properties of monoclonal antibodies

Immunoglobulin G-based monoclonal antibodies (mAbs) have become a dominant class of biotherapeutics in recent decades. Approved antibodies are mainly of the subclasses IgG1, IgG2, and IgG4, as well as their derivatives. Over the decades, the selection of IgG subclass has frequently been based on the...

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Main Authors: Yu Tang (Author), Paul Cain (Author), Victor Anguiano (Author), James J. Shih (Author), Qing Chai (Author), Yiqing Feng (Author)
Format: Book
Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
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