Modifications on the Tetrahydroquinoline Scaffold Targeting a Phenylalanine Cluster on GPER as Antiproliferative Compounds against Renal, Liver and Pancreatic Cancer Cells

• المؤلفون الرئيسيون: David Méndez-Luna (مؤلف), Loreley Araceli Morelos-Garnica (مؤلف), Juan Benjamín García-Vázquez (مؤلف), Martiniano Bello (مؤلف), Itzia Irene Padilla-Martínez (مؤلف), Manuel Jonathan Fragoso-Vázquez (مؤلف), Alfonso Dueñas González (مؤلف), Nuria De Pedro (مؤلف), José Antonio Gómez-Vidal (مؤلف), Humberto Lubriel Mendoza-Figueroa (مؤلف), José Correa-Basurto (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2021-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

The implementation of chemo- and bioinformatics tools is a crucial step in the design of structure-based drugs, enabling the identification of more specific and effective molecules against cancer without side effects. In this study, three new compounds were designed and synthesized with suitable abs...