Atomic Pairwise Distribution Function Analysis of the Amorphous Phase Prepared by Different Manufacturing Routes

• Main Authors: Thomas Rades (Author), Marja Savolainen (Author), Jukka Rantanen (Author), Vishal Koradia (Author), Johan P. Boetker (Author)
• Format: Book
• Published: MDPI AG, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Amlodipine besilate, a calcium channel antagonist, exists in several solid forms. Processing of anhydrate and dihydrate forms of this drug may lead to solid state changes, and is therefore the focus of this study. Milling was performed for the anhydrate form, whereas the dihydrate form was subjected...