High-Throughput mRNA Sequencing Reveals Potential Therapeutic Targets of Febuxostat in Secondary Injury After Intracerebral Hemorrhage

• Main Authors: Xueyan Wang (Author), Chenyu Zhang (Author), Yuwen Li (Author), Ting Xu (Author), Jin Xiang (Author), Yang Bai (Author), Ying Zhang (Author), Qi Wang (Author), Tiejun Zhang (Author), Linchuan Liao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Febuxostat is a urate-lowering medication for the treatment of patients with gout. This study was performed to elucidate the effects and underlying mechanisms of febuxostat on neuronal injury induced by intracerebral hemorrhage (ICH) in mice. The results showed that the administration of febuxostat...