Cytokine responses to novel antigens in an Indian population living in an area endemic for visceral leishmaniasis.

• Main Authors: Om Prakash Singh (Author), Carmel B Stober (Author), Abhishek Kr Singh (Author), Jenefer M Blackwell (Author), Shyam Sundar (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There are no effective vaccines for visceral leishmaniasis (VL), a neglected parasitic disease second only to malaria in global mortality. We previously identified 14 protective candidates in a screen of 100 Leishmania antigens as DNA vaccines in mice. Here we employ whole blood assays to evaluate h...