Small Molecule-Peptide Conjugates as Dimerization Inhibitors of <i>Leishmania infantum</i> Trypanothione Disulfide Reductase
Trypanothione disulfide reductase (TryR) is an essential homodimeric enzyme of trypanosomatid parasites that has been validated as a drug target to fight human infections. Using peptides and peptidomimetics, we previously obtained proof of concept that disrupting protein-protein interactions at the...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
| Published: |
MDPI AG,
2021-07-01T00:00:00Z.
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