A Drosophila XPD model links cell cycle coordination with neuro-development and suggests links to cancer

• 主要な著者: Karin Stettler (著者), Xiaoming Li (著者), Björn Sandrock (著者), Sophie Braga-Lagache (著者), Manfred Heller (著者), Lutz Dümbgen (著者), Beat Suter (著者)
• フォーマット: 図書
• 出版事項: The Company of Biologists, 2015-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

XPD functions in transcription, DNA repair and in cell cycle control. Mutations in human XPD (also known as ERCC2) mainly cause three clinical phenotypes: xeroderma pigmentosum (XP), Cockayne syndrome (XP/CS) and trichothiodystrophy (TTD), and only XP patients have a high predisposition to developin...