Blood transcriptomics to facilitate diagnosis and stratification in pediatric rheumatic diseases - a proof of concept study

• Main Authors: My Kieu Ha (Author), Esther Bartholomeus (Author), Luc Van Os (Author), Julie Dandelooy (Author), Julie Leysen (Author), Olivier Aerts (Author), Vasiliki Siozopoulou (Author), Eline De Smet (Author), Jan Gielen (Author), Khadija Guerti (Author), Michel De Maeseneer (Author), Nele Herregods (Author), Bouchra Lechkar (Author), Ruth Wittoek (Author), Elke Geens (Author), Laura Claes (Author), Mahmoud Zaqout (Author), Wendy Dewals (Author), Annelies Lemay (Author), David Tuerlinckx (Author), David Weynants (Author), Koen Vanlede (Author), Gerlant van Berlaer (Author), Marc Raes (Author), Helene Verhelst (Author), Tine Boiy (Author), Pierre Van Damme (Author), Anna C. Jansen (Author), Marije Meuwissen (Author), Vito Sabato (Author), Guy Van Camp (Author), Arvid Suls (Author), Jutte Van der Werff ten Bosch (Author), Joke Dehoorne (Author), Rik Joos (Author), Kris Laukens (Author), Pieter Meysman (Author), Benson Ogunjimi (Author)
• Format: Book
• Published: BMC, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Transcriptome profiling of blood cells is an efficient tool to study the gene expression signatures of rheumatic diseases. This study aims to improve the early diagnosis of pediatric rheumatic diseases by investigating patients' blood gene expression and applying machine lea...