miR-146b-5p Enhances the Sensitivity of NSCLC to EGFR Tyrosine Kinase Inhibitors by Regulating the IRAK1/NF-κB Pathway

• मुख्य लेखकों: Yi-Nan Liu (लेखक), Meng-Feng Tsai (लेखक), Shang-Gin Wu (लेखक), Tzu-Hua Chang (लेखक), Tzu-Hsiu Tsai (लेखक), Chien-Hung Gow (लेखक), Hsin-Yi Wang (लेखक), Jin-Yuan Shih (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2020-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Although patients with non-small cell lung cancer harboring activating mutations in the epidermal growth factor receptor (EGFR) show good clinical response to EGFR tyrosine kinase inhibitors (TKIs), patients eventually develop acquired resistance. Previous studies have shown that several microRNAs (...