miR-146b-5p Enhances the Sensitivity of NSCLC to EGFR Tyrosine Kinase Inhibitors by Regulating the IRAK1/NF-κB Pathway

• Main Authors: Yi-Nan Liu (Author), Meng-Feng Tsai (Author), Shang-Gin Wu (Author), Tzu-Hua Chang (Author), Tzu-Hsiu Tsai (Author), Chien-Hung Gow (Author), Hsin-Yi Wang (Author), Jin-Yuan Shih (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although patients with non-small cell lung cancer harboring activating mutations in the epidermal growth factor receptor (EGFR) show good clinical response to EGFR tyrosine kinase inhibitors (TKIs), patients eventually develop acquired resistance. Previous studies have shown that several microRNAs (...