S-allyl-l-cysteine attenuates bleomycin-induced pulmonary fibrosis and inflammation via AKT/NF-κB signaling pathway in mice

• Main Authors: Yunjuan Nie (Author), Kaikai Yu (Author), Boyu Li (Author), Yudong Hu (Author), Hui Zhang (Author), Ruiting Xin (Author), Yue Xiong (Author), Peng Zhao (Author), Gaoshang Chai (Author)
• Format: Book
• Published: Elsevier, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal lung disease characterized by inflammation, multifocal fibrotic lesions and excessive collagen deposition with limited therapies. As a major bioactive compound in garlic, S-allyl-l-cysteine (SAC) is a neuroprotective drug candidate to p...