The host-targeting compound peruvoside has a broad-spectrum antiviral activity against positive-sense RNA viruses

• Main Authors: Kan Xing Wu (Author), Thinesshwary Yogarajah (Author), Marcus Wing Choy Loe (Author), Parveen Kaur (Author), Regina Ching Hua Lee (Author), Chee Keng Mok (Author), Yi Hao Wong (Author), Patchara Phuektes (Author), Li Sze Yeo (Author), Vincent T.K. Chow (Author), Yong Wah Tan (Author), Justin Jang Hann Chu (Author)
• Format: Book
• Published: Elsevier, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Positive-sense RNA viruses modify intracellular calcium stores, endoplasmic reticulum and Golgi apparatus (Golgi) to generate membranous replication organelles known as viral factories. Viral factories provide a conducive and substantial enclave for essential virus replication via concentrating nece...