In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N1,N3-bis-(1-hydrazinyl-1-oxopropan-2-yl) isophthalamide

• Hoofdauteurs: Asmaa F. Kassem (Auteur), Gaber O. Moustafa (Auteur), Eman S. Nossier (Auteur), Hemat S. Khalaf (Auteur), Marwa M. Mounier (Auteur), Suliman A. Al-Yousef (Auteur), Sabry Y. Mahmoud (Auteur)
• Formaat: Boek
• Gepubliceerd in: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

A series of N1,N3-bis (1-oxopropan-2-yl) isophthalamide-based derivatives 4-16 were prepared and their structures were confirmed by different spectral tools. The cytotoxic potentiality of novel compounds 4-16 was assessed by the MTT assay method on colon, lung and breast tumour cell lines. Compound...