NPM1 and FLT3 mutations in acute myeloid leukemia with normal karyotype: Indian perspective

• Main Authors: Sudha Sazawal (Author), Neha Singh (Author), Sonal Jain (Author), Sunita Chhikara (Author), Rekha Chaubey (Author), Jina Bhattacharyya (Author), Kandarpa Kr Saikia (Author), Manoranjan Mahapatra (Author), Renu Saxena (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: FLT3-ITD and NPM1 mutations are considered to be the major determinants of the patient response to therapy and outcome. The primary aim of this study was to establish the correlation between these molecular mutations and the clinico-hematologic parameters as well as the prognostic outcom...