Spontaneous Formation of Melanin from Dopamine in the Presence of Iron

• Main Authors: David M. Hedges (Author), Jordan T. Yorgason (Author), Andrew W. Perez (Author), Nathan D. Schilaty (Author), Benjamin M. Williams (Author), Richard K. Watt (Author), Scott C. Steffensen (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parkinson's disease is associated with degeneration of neuromelanin (NM)-containing substantia nigra dopamine (DA) neurons and subsequent decreases in striatal DA transmission. Dopamine spontaneously forms a melanin through a process called melanogenesis. The present study examines conditions t...