Depletion of regulatory T cells enhancing the anti-tumor effect of in situ vaccination in solid tumors

• Egile Nagusiak: Ya-Jia Xie (Egilea), Sha Tian (Egilea), Min Huang (Egilea), Lin-Lin Lu (Egilea), Zhong-Qiu Liu (Egilea), Jun-Hui Chen (Egilea), Xing-Xing Fan (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2024-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The emergence of immune checkpoint inhibitors (ICIs) has revolutionized the clinical treatment for tumor. However, the low response rate of ICIs remains the major obstacle for curing patients and effective approaches for patients with primary or secondary resistance to ICIs remain lacking. In this s...