Bayesian estimation in NONMEM

• Main Authors: Curtis K. Johnston (Author), Timothy Waterhouse (Author), Matthew Wiens (Author), John Mondick (Author), Jonathan French (Author), William R. Gillespie (Author)
• Format: Book
• Published: Wiley, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Bayesian estimation is a powerful but underutilized tool for answering drug development questions. In this tutorial, the principles of Bayesian model development, assessment, and prior selection will be outlined. An example pharmacokinetic (PK) model will be used to demonstrate the implemen...