Dynamic duo: Kir6 and SUR in KATP channel structure and function

• Main Authors: Bruce L. Patton (Author), Phillip Zhu (Author), Assmaa ElSheikh (Author), Camden M. Driggers (Author), Show-Ling Shyng (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTKATP channels are ligand-gated potassium channels that couple cellular energetics with membrane potential to regulate cell activity. Each channel is an eight subunit complex comprising four central pore-forming Kir6 inward rectifier potassium channel subunits surrounded by four regulatory su...