An Integrated Pharmacokinetic Study of an Acanthopanax senticosus Extract Preparation by Combination of Virtual Screening, Systems Pharmacology, and Multi-Component Pharmacokinetics in Rats

• Những tác giả chính: Peiying Shi (Tác giả), Yunjiao Xie (Tác giả), Rongfang Xie (Tác giả), Zuan Lin (Tác giả), Hong Yao (Tác giả), Shuang Wu (Tác giả)
• Định dạng: Sách
• Được phát hành: Frontiers Media S.A., 2020-08-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

In this paper, the integrated pharmacokinetics (PK) of an Acanthopanax senticosus extract preparation (ASEP, named as Ciwujia injection in clinic in China) was explored by combining with multi-component PK in rats, virtual screening, systems pharmacology and molecular docking. Firstly, the ingredien...