High water intake induces primary cilium elongation in renal tubular cells

• Main Authors: Min Jung Kong (Author), Sang Jun Han (Author), Sung Young Seu (Author), Ki-Hwan Han (Author), Joshua H. Lipschutz (Author), Kwon Moo Park (Author)
• Format: Book
• Published: The Korean Society of Nephrology, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background The primary cilium protrudes from the cell surface and functions as a mechanosensor. Recently, we found that water intake restriction shortens the primary cilia of renal tubular cells, and a blockage of the shortening disturbs the ability of the kidneys to concentrate urine. Here, we inve...