Bioavailability of Melatonin after Administration of an Oral Prolonged-Release Tablet and an Immediate-Release Sublingual Spray in Healthy Male Volunteers

• المؤلفون الرئيسيون: Samira Ait Abdellah (مؤلف), Véronique Raverot (مؤلف), Caroline Gal (مؤلف), Isabelle Guinobert (مؤلف), Valérie Bardot (مؤلف), Claude Blondeau (مؤلف), Bruno Claustrat (مؤلف)
• التنسيق: كتاب
• منشور في: Adis, Springer Healthcare, 2023-07-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background The benefit of exogenous melatonin is based on its bioavailability, which depends on the galenic form, the route of administration, the dosage, and the individual absorption and rate of hepatic metabolism. Objective The objective of this study is to investigate the bioavailabilit...