Extracellular Vesicles from Adipose-Derived Mesenchymal Stem/Stromal Cells Accelerate Migration and Activate AKT Pathway in Human Keratinocytes and Fibroblasts Independently of miR-205 Activity

• Главные авторы: Andrea da Fonseca Ferreira (Автор), Pricila da Silva Cunha (Автор), Virgínia Mendes Carregal (Автор), Priscila de Cássia da Silva (Автор), Marcelo Coutinho de Miranda (Автор), Marianna Kunrath-Lima (Автор), Mariane Izabella Abreu de Melo (Автор), Camila Cristina Fraga Faraco (Автор), Joana Lobato Barbosa (Автор), Frédéric Frezard (Автор), Vivian Resende (Автор), Michele Angela Rodrigues (Автор), Alfredo Miranda de Goes (Автор), Dawidson Assis Gomes (Автор)
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• Опубликовано: Hindawi Limited, 2017-01-01T00:00:00Z.
• Предметы: article
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Mesenchymal stem/stromal cells (MSCs) are promising tools in cell therapy. They secrete extracellular vesicles (EVs) that carry different classes of molecules that can promote skin repair, but the mechanisms are poorly understood. Skin wound healing is a complex process that requires the activity of...