CD97 inhibits osteoclast differentiation via Rap1a/ERK pathway under compression

• Main Authors: Wen Wang (Author), Qian Wang (Author), Shiying Sun (Author), Pengfei Zhang (Author), Yuyu Li (Author), Weimin Lin (Author), Qiwen Li (Author), Xiao Zhang (Author), Zhe Ma (Author), Haiyan Lu (Author)
• Format: Book
• Published: Nature Publishing Group, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Acceleration of tooth movement during orthodontic treatment is challenging, with osteoclast-mediated bone resorption on the compressive side being the rate-limiting step. Recent studies have demonstrated that mechanoreceptors on the surface of monocytes/macrophages, especially adhesion G pr...