Etodolac transdermal cubosomes for the treatment of rheumatoid arthritis: ex vivo permeation and in vivo pharmacokinetic studies

• Main Authors: Salwa Salah (Author), Azza A. Mahmoud (Author), Amany O. Kamel (Author)
• Format: Bog
• Udgivet: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Fag: article
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In this study, transdermal etodolac-loaded cubosomes were developed in order to relieve patient pain and joints stiffness by providing stable etodolac concentration at the targeting sites through controlled drug delivery via the noninvasive skin route with more sustaining and less frequent dosing. D...