Dorsomorphin attenuates ABCG2-mediated multidrug resistance in colorectal cancer

• Main Authors: Xiao-Peng Li (Author), Liang-Qi Cao (Author), Ze-Zhong Yu (Author), Ke He (Author), Peng-Bo Ding (Author), Ji-Sheng Li (Author), Yi-Yao Shan (Author), Yu-Bin Su (Author), Zhong-Min Yuan (Author), Zhi Shi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Colorectal cancer is a common malignant tumor with high mortality, for which chemotherapy resistance is one of the main reasons. The high expression of ABCG2 in the cancer cells and expulsion of anticancer drugs directly cause multidrug resistance (MDR). Therefore, the development of new ABCG2 inhib...