Immunogenicity induced by the use of alternative vaccine platforms to deal with vaccine shortages in a low- to middle-income country: Results of two randomized clinical trials

• Main Authors: Alejandro Macchia (Author), Daniel Ferrante (Author), María Belén Bouzas (Author), Patricia Angeleri (Author), Cristián Biscayart (Author), Jorge Geffner (Author), Lilia Mammana (Author), Inés Zapiola (Author), Eduardo Luis López (Author), Angela Gentile (Author), Augusto Varese (Author), Ignacio Mazzitelli (Author), Facundo Di Diego García (Author), Deborah Sharff (Author), Verónica Lucconi (Author), Paula Sujansky (Author), Javier Mariani (Author), Fernán González Bernaldo de Quirós (Author)
• Format: Book
• Published: Elsevier, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Background: Shortages of component two of Sputnik V vaccine (rAd5) are delaying the possibility of achieving full immunisation. The immunogenic response associated with the use of alternative schemes to complete the scheme was not explored. Methods: We did two non-inferiority randomized cli...