The Damaging Outcome of the POLAR Phase III Trials Was Due to Avoidable Time-Dependent Redox Interaction between Oxaliplatin and PledOx

On 2 July 2021, highly negative results were reported from the POLAR A and M phase III trials in patients with colorectal cancer, treated with an oxaliplatin-based regimen and co-treated with calmangafodipir (CaM; PledOx<sup>®</sup>; PledPharma AB/Egetis Therapeutics AB) or placebo. The...

Full description

Saved in:
Bibliographic Details
Main Authors: Jan Olof G. Karlsson (Author), Per Jynge (Author), Louis J. Ignarro (Author)
Format: Book
Published: MDPI AG, 2021-12-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available