20(S)-Protopanaxatriol promotes the binding of P53 and DNA to regulate the antitumor network via multiomic analysis

• Main Authors: Zhihua Wang (Author), Wenbo Wu (Author), Xiangchen Guan (Author), Shuang Guo (Author), Chaowen Li (Author), Ruixue Niu (Author), Jie Gao (Author), Min Jiang (Author), Liping Bai (Author), Elaine Laihan Leung (Author), Yuanyuan Hou (Author), Zhihong Jiang (Author), Gang Bai (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although the tumor suppressor P53 is known to regulate a broad network of signaling pathways, it is still unclear how certain drugs influence these P53 signaling networks. Here, we used a comprehensive single-cell multiomics view of the effects of ginsenosides on cancer cells. Transcriptome and prot...