Development and Optimization of a Redox Enzyme-Based Fluorescence Biosensor for the Identification of MsrB1 Inhibitors

MsrB1 is a thiol-dependent enzyme that reduces protein methionine-<i>R</i>-sulfoxide and regulates inflammatory response in macrophages. Therefore, MsrB1 could be a promising therapeutic target for the control of inflammation. To identify MsrB1 inhibitors, we construct a redox protein-ba...

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Main Authors: Hyun Bo Shim (Author), Hyunjeong Lee (Author), Hwa Yeon Cho (Author), Young Ho Jo (Author), Lionel Tarrago (Author), Hyunggee Kim (Author), Vadim N. Gladyshev (Author), Byung Cheon Lee (Author)
Format: Book
Published: MDPI AG, 2024-11-01T00:00:00Z.
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3rd Floor Main Library

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