Pathophysiology of NSAID-Associated Intestinal Lesions in the Rat: Luminal Bacteria and Mucosal Inflammation as Targets for Prevention

• Main Authors: Rocchina Colucci (Author), Carolina Pellegrini (Author), Matteo Fornai (Author), Erika Tirotta (Author), Luca Antonioli (Author), Cecilia Renzulli (Author), Emilia Ghelardi (Author), Elena Piccoli (Author), Daniela Gentile (Author), Laura Benvenuti (Author), Gianfranco Natale (Author), Federica Fulceri (Author), Pablo Palazón-Riquelme (Author), Gloria López-Castejón (Author), Corrado Blandizzi (Author), Carmelo Scarpignato (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Non-steroidal anti-inflammatory drugs (NSAIDs) can damage the small intestine, mainly through an involvement of enteric bacteria. This study examined the pathophysiology of NSAID-associated intestinal lesions in a rat model of diclofenac-enteropathy and evaluated the effect of rifaximin on small bow...