Fluorescent in Situ Hybridization and Real-Time Quantitative Polymerase Chain Reaction to Evaluate HER-2/neu Status in Breast Cancer

• Main Authors: Fatemeh Homaei Shandiz (Author), Azar Fani (Author), Sepideh Shakeri (Author), Maryam Sheikhi (Author), Abouzar Ramezani Farkhani (Author), Arezoo Shajiei (Author), Hossein Ayatollahi (Author)
• Format: Book
• Published: Iranian Society of Pathology, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background:Breast cancer remains the most common and second lethal cancer in females. HER-2/neu is one of the most important amplified oncogene in breast cancer. The amplification of HER-2 is correlated with decreased survival, metastasis, and early recurrence.  The amplification of HER-2/neu gene a...