Placental transcriptome analysis of hypertensive pregnancies identifies distinct gene expression profiles of preeclampsia superimposed on chronic hypertension

• Главные авторы: Ashley M. Hesson (Автор), Elizabeth S. Langen (Автор), Olesya Plazyo (Автор), Johann E. Gudjonsson (Автор), Santhi K. Ganesh (Автор)
• Формат: ‌
• Опубликовано: BMC, 2023-05-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Abstract Background The pathogenesis of preeclampsia superimposed on chronic hypertension (SI) is poorly understood relative to preeclampsia (PreE) occurring in pregnant people without chronic hypertension. Placental transcriptomes in pregnancies complicated by PreE and SI have not been previously c...