Combination of umbilical cord mesenchymal stem cells and standard immunosuppressive regimen for pediatric patients with severe aplastic anemia

• Main Authors: Yang Lan (Author), Fang Liu (Author), Lixian Chang (Author), Lipeng Liu (Author), Yingchi Zhang (Author), Meihui Yi (Author), Yuli Cai (Author), Jing Feng (Author), Zhibo Han (Author), Zhongchao Han (Author), Xiaofan Zhu (Author)
• Format: Book
• Published: BMC, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Defects of bone marrow mesenchymal stem cells (BM-MSCs) in proliferation and differentiation are involved in the pathophysiology of aplastic anemia (AA). Infusion of umbilical cord mesenchymal stem cells (UC-MSCs) may improve the efficacy of immunosuppressive therapy (IST) in chi...