Optimisation of the Manufacturing Process of Organic-Solvent-Free Omeprazole Enteric Pellets for the Paediatric Population: Full Factorial Design

• Main Authors: Khadija Rouaz- (Author), Encarnación García-Montoya (Author), Andrea López-Urbano (Author), Miquel Romero-Obon (Author), Blanca Chiclana-Rodríguez (Author), Alex Fraschi-Nieto (Author), Anna Nardi-Ricart (Author), Marc Suñé-Pou (Author), Josep María Suñé-Negre (Author), Pilar Pérez-Lozano (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liquid formulations are mostly used in the paediatric population. However, with certain active pharmaceutical ingredients (APIs), it is very difficult to guarantee quality and stability; this is the case, for example, with omeprazole. Omeprazole is used as a model drug due to the lack of a paediatri...